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Category: Science

A fun take on the latest science news with enough data to sink your teeth into. Lagrange Point goes beyond the glossy summary and gets in depth with the research from across the world.

September 21, 2020

Episode 397 - Ignobel Prize ‘20 - Physics

We celebrate the Ignobel Prizes once again, and this year we take a deep dive into the Physics prize for 2020. Faraday waves (standing waves in liquids or liquid filled objects) look pretty, but can anything filled with like have one? What about a worm? Can you make Faraday waves and resonant frequencies in Worms? What happens when a laser, a worm, and a speaker go into a lab? The result is an Ignobel Prize.

  1. Maksymov, I.S., Pototsky, A. Excitation of Faraday-like body waves in vibrated living earthworms. Sci Rep 10, 8564 (2020). https://doi.org/10.1038/s41598-020-65295-4
  2. 2020 Ceremony. (2020, September 18). Retrieved September 18, 2020, from https://www.improbable.com/ig-about/the-30th-first-annual-ig-nobel-prize-ceremony/
September 14, 2020

Episode 396 - Is that food safe to eat

Is that food safe to eat? How can you tell if food has gone bad beyond just reading a date? Ever been confused by best before or use by? A new type of label could make it a mater of colors. Color based labels could help detect if your food has gone bad or is contaminated by bacteria. How can we study the microbes that live inside our intestines? The gut microbiome is incredibly fascinating but difficult to study without damaging it. A tiny pill that takes snapshots of micro organisms inside your stomach as it passes through.

  1. Doyoon Kim, Yunteng Cao, Dhanushkodi Mariappan, Michael S. Bono Jr., A. John Hart, Benedetto Marelli. A Microneedle Technology for Sampling and Sensing Bacteria in the Food Supply ChainAdvanced Functional Materials, 2020 DOI: 10.1002/adfm.202005370
  2. Lu Chen, Lina Gruzinskyte, Steffen Lynge Jørgensen, Anja Boisen, Sarvesh Kumar Srivastava. An Ingestible Self-Polymerizing System for Targeted Sampling of Gut Microbiota and BiomarkersACS Nano, 2020; DOI: 10.1021/acsnano.0c05426
September 7, 2020

Episode 395 - Learning from unusual plants

Plants are incredibly important for a healthy planet and a well fed population. How can we improve our plants by learning from some unusual ones? You normally picture a plant with lots of leaves, but some only grow one lonely leaf. Deep in limestone caves of South East Asia grows a plant with only ever one giant leaf. How can a plant survive with just one leaf and why does it continue to grow in size? What can we learn by studying the root systems of different plants? Can breeding plants to have more flexible roots lead to more resilient crops?

  1. Ayaka Kinoshita, Hiroyuki Koga, Hirokazu Tsukaya. Expression Profiles of ANGUSTIFOLIA3 and SHOOT MERISTEMLESS, Key Genes for Meristematic Activity in a One-Leaf Plant Monophyllaea glabra, Revealed by Whole-Mount In Situ Hybridization. Frontiers in Plant Science, 2020; 11 DOI: 10.3389/fpls.2020.01160
  2. James D. Burridge, Harini Rangarajan, Jonathan P. Lynch. Comparative phenomics of annual grain legume root architecture. Crop Science, 2020; DOI: 10.1002/csc2.20241
August 24, 2020

Episode 393 - Microbial life in a teaspoon of the ocean

Life in the ocean is more than just fish, whales and squid, it goes down to a microbial level. We can learn a lot about the health of a whole reef system by studying microbial life in the water. Just one teaspoon of the ocean contains thousands of unique microbes. The ocean currents carry and mix ocean microbes. What makes a healthy reef? Well take a look at the microbes. How can nutrient and soil runoff damage a reef?

  1. Maria G. Pachiadaki, Julia M. Brown, Joseph Brown, Oliver Bezuidt, Paul M. Berube, Steven J. Biller, Nicole J. Poulton, Michael D. Burkart, James J. La Clair, Sallie W. Chisholm, Ramunas Stepanauskas. Charting the Complexity of the Marine Microbiome through Single-Cell GenomicsCell, 2019; 179 (7): 1623 DOI: 10.1016/j.cell.2019.11.017
  2. Laura Weber, Patricia González‐Díaz, Maickel Armenteros, Víctor M. Ferrer, Fernando Bretos, Erich Bartels, Alyson E. Santoro, Amy Apprill. Microbial signatures of protected and impacted Northern Caribbean reefs: changes from Cuba to the Florida KeysEnvironmental Microbiology, 2019; DOI: 10.1111/1462-2920.14870
August 17, 2020

Episode 392 - How brains process and overload of information

Your senses bombard your brain with an overload of information, so how does it process it all? How does y our brain decide what information to focus on? The brain can focus voluntarily or involuntarily on regions of an image to best process it. How does your brain decide which parts of an image to focus on? What part of your brain helps gatekeep the waves of sensory input before it gets processed? How can your brain help regulate and manage an overload of sensory inputs.

  1. Antonio Fernández, Marisa Carrasco. Extinguishing Exogenous Attention via Transcranial Magnetic StimulationCurrent Biology, 2020; DOI: 10.1016/j.cub.2020.07.068
  2. Yinqing Li, Violeta G. Lopez-Huerta, Xian Adiconis, Kirsten Levandowski, Soonwook Choi, Sean K. Simmons, Mario A. Arias-Garcia, Baolin Guo, Annie Y. Yao, Timothy R. Blosser, Ralf D. Wimmer, Tomomi Aida, Alexander Atamian, Tina Naik, Xuyun Sun, Dasheng Bi, Diya Malhotra, Cynthia C. Hession, Reut Shema, Marcos Gomes, Taibo Li, Eunjin Hwang, Alexandra Krol, Monika Kowalczyk, João Peça, Gang Pan, Michael M. Halassa, Joshua Z. Levin, Zhanyan Fu, Guoping Feng. Distinct subnetworks of the thalamic reticular nucleusNature, 2020; DOI: 10.1038/s41586-020-2504-5
July 27, 2020

Episode 389 - Chronic Pain, Ears, Long lasting Electrodes

Treating chronic pain through tiny electrodes in your ear. Can 3 phase like stimulating of nerves in your eye help treat chronic pain? Mapping out the inside of the ear in incredibly fine detail can help treat chronic pain. Fine tuning tiny electrodes inside the ear can help relieve chronic pain. Using a printer, tattoo paper and polymers to make long lasting electrodes. Flexible, thin and long lasting electrodes can make it easier to study the brain and the heart. Studying the brain over the long term just got easier with tattoo paper based electrodes.

  1. Babak Dabiri, Stefan Kampusch, Stefan H. Geyer, Van Hoang Le, Wolfgang J. Weninger, Jozsef Constantin Széles, Eugenijus Kaniusas. High-Resolution Episcopic Imaging for Visualization of Dermal Arteries and Nerves of the Auricular Cymba Conchae in HumansFrontiers in Neuroanatomy, 2020; 14 DOI: 10.3389/fnana.2020.00022
  2. Laura M. Ferrari, Usein Ismailov, Jean-Michel Badier, Francesco Greco, Esma Ismailova. Conducting polymer tattoo electrodes in clinical electro- and magneto-encephalographynpj Flexible Electronics, 2020; 4 (1) DOI: 10.1038/s41528-020-0067-z
July 20, 2020

Episode 388 - Cleaning, drinking and shaping water

Making water safe to drink, from evaporation to treatment. How do you simply evaporate water to make it safe? A piece of aluminium and a laser can hold the key to providing cheap and safe drinking water to the world. Pharmaceutical waste can build up in waster water, so how can it be treated? How can two little electrodes deal with the problem of pharmaceutical waste in water? Changing the course of a river can have huge consequences. What can we learn by studying the changes caused by the Panama Canal?

  1. Subhash C. Singh, Mohamed ElKabbash, Zilong Li, Xiaohan Li, Bhabesh Regmi, Matthew Madsen, Sohail A. Jalil, Zhibing Zhan, Jihua Zhang, Chunlei Guo. Solar-trackable super-wicking black metal panel for photothermal water sanitationNature Sustainability, 2020; DOI: 10.1038/s41893-020-0566-x
  2. Yassine Ouarda, Clément Trellu, Geoffroy Lesage, Matthieu Rivallin, Patrick Drogui, Marc Cretin. Electro-oxidation of secondary effluents from various wastewater plants for the removal of acetaminophen and dissolved organic matterScience of The Total Environment, 2020; 738: 140352 DOI: 10.1016/j.scitotenv.2020.140352
  3. Jorge Salgado, María I. Vélez, Catalina González-Arango, Neil L. Rose, Handong Yang, Carme Huguet, Juan S. Camacho, Aaron O'Dea. A century of limnological evolution and interactive threats in the Panama Canal: Long-term assessments from a shallow basinScience of The Total Environment, 2020; 729: 138444 DOI: 10.1016/j.scitotenv.2020.138444
July 6, 2020

Episode 386 - T-rex, Raptors and Giant Squid go a hunting

How fast did T-Rex really go? Was it a sprinter or an endurance runner? Being chased by a T-Rex is scary, but you have to be ready for a marathon not a sprint. T-Rex's long legs helped it be efficient rather than speedy. Did raptors hunt in packs or just near each other? What links Komodo dragons and hunting raptors? Can we figure out if raptors hunted in packs by studying their teeth? Can Komodo dragons help bust Jurrassic Park myths? We also find out about an epic battle between Giant squid and a fish trapped for eternity as fossils.

  1. T. Alexander Dececchi, Aleksandra M. Mloszewska, Thomas R. Holtz, Michael B. Habib, Hans C. E. Larsson. The fast and the frugal: Divergent locomotory strategies drive limb lengthening in theropod dinosaursPLOS ONE, 2020; 15 (5): e0223698 DOI: 10.1371/journal.pone.0223698
  2. J.A. Frederickson, M.H. Engel, R.L. Cifelli. Ontogenetic dietary shifts in Deinonychus antirrhopus (Theropoda; Dromaeosauridae): Insights into the ecology and social behavior of raptorial dinosaurs through stable isotope analysisPalaeogeography, Palaeoclimatology, Palaeoecology, 2020; 109780 DOI: 10.1016/j.palaeo.2020.109780
  3. University of Plymouth. (2020, May 6). Fossil reveals evidence of 200-million-year-old 'squid' attack. ScienceDaily. Retrieved May 15, 2020 from www.sciencedaily.com/releases/2020/05/200506133625.htm
June 22, 2020

Episode 384 - Plants regenerating and fighting off invaders

How do plants manage to recover from damage or fungal attacks? What happens when you shoot a laser at some cress? Studying the way plants respond to damage helps us understand their regeneration methods. Plant cells can regenerate to recover from damage, but what controls this process? Fighting off a fungal invasion means an arms race between plants and fungus. Plants like cabbage use a special mustard oil bomb to fight back against fungal invaders. Fungal invaders like white mold can render even the most sophisticate plant defences useless.

  1. Lukas Hoermayer, Juan Carlos Montesinos, Petra Marhava, Eva Benková, Saiko Yoshida, Jiří Friml. Wounding-induced changes in cellular pressure and localized auxin signalling spatially coordinate restorative divisions in rootsProceedings of the National Academy of Sciences, 2020; 202003346 DOI: 10.1073/pnas.2003346117
  2. Jingyuan Chen, Chhana Ullah, Michael Reichelt, Franziska Beran, Zhi-Ling Yang, Jonathan Gershenzon, Almuth Hammerbacher, Daniel G. Vassão. The phytopathogenic fungus Sclerotinia sclerotiorum detoxifies plant glucosinolate hydrolysis products via an isothiocyanate hydrolaseNature Communications, 2020; 11 (1) DOI: 10.1038/s41467-020-16921-2
June 8, 2020

Episode 382 - Animals keeping watch on our environment

Animals can help us monitor our environment for pollution. From silicon dog tags to tiger snakes in wetlands, animals can help us monitor pollution. How can silicon dog tags help protect humans from environmental pollutants? Cleaning up an oil spill is tricky, but with the right materials it's easy as wringing a sponge. Water hating but Oil loving magnetic sponges can help clean up after oil spills. How do Tiger snakes help us find the cleanest wetlands? Just how clean are urban wetlands?

  1. Catherine F. Wise, Stephanie C. Hammel, Nicholas Herkert, Jun Ma, Alison Motsinger-Reif, Heather M. Stapleton, Matthew Breen. Comparative Exposure Assessment Using Silicone Passive Samplers Indicates That Domestic Dogs Are Sentinels To Support Human Health Research. Environmental Science & Technology, 2020; DOI: 10.1021/acs.est.9b06605
  2. D. C. Lettoof, P. W. Bateman, F. Aubret, M. M. Gagnon. The Broad-Scale Analysis of Metals, Trace Elements, Organochlorine Pesticides and Polycyclic Aromatic Hydrocarbons in Wetlands Along an Urban Gradient, and the Use of a High Trophic Snake as a Bioindicator. Archives of Environmental Contamination and Toxicology, 2020; 78 (4): 631 DOI: 10.1007/s00244-020-00724-z
  3. Vikas Nandwana, Stephanie M. Ribet, Roberto D. Reis, Yuyao Kuang, Yash More, Vinayak P. Dravid. OHM Sponge: A Versatile, Efficient, and Ecofriendly Environmental Remediation Platform. Industrial & Engineering Chemistry Research, 2020; DOI: 10.1021/acs.iecr.0c01493
June 1, 2020

Episode 381 - A good nights sleep and finding it hard to wake up in the morning

Finding it hard to wake up in the morning when it's cold? Don't worry you're not alone. What can we Fruit Flies teach us about wanting to stay in bed especially when it's cold outside? How do the cycles of temperature and light impact sleep? Is the right temperature key to a good night's rest? Is the optimum temperature hard coded in creatures brain or is it all relative? Getting a good night's sleep is important for keeping your brain healthy. What can zebrafish and fruit flies help us understand about getting a good night's sleep? Is there a connection between a good night's sleep and cleaning out unwanted proteins in your brain?

  1. Michael H. Alpert, Dominic D. Frank, Evan Kaspi, Matthieu Flourakis, Emanuela E. Zaharieva, Ravi Allada, Alessia Para, Marco Gallio. A Circuit Encoding Absolute Cold Temperature in Drosophila. Current Biology, 2020; DOI: 10.1016/j.cub.2020.04.038
  2. Sarah Ly, Daniel A. Lee, Ewa Strus, David A. Prober, Nirinjini Naidoo. Evolutionarily Conserved Regulation of Sleep by the Protein Translational Regulator PERK. Current Biology, 2020; DOI: 10.1016/j.cub.2020.02.030
May 18, 2020

Episode 379 - Colourful feathers on dinosaurs and birds today

Colourful feathers on dinosaurs and their descendants. Sleek, fast, with sharp claws and iridescent feathers, Cassowaries are almost like dinosaurs. How do the cassowaries manage to get that special sheen on their feathers? What gives cassowaries they're menacing iridescence? Long flowing rainbow feathers, all wrapped around a small creature the size of a duck, hardly a terrifying image of a dinosaur. What connects a small duck like dinosaur with a hummingbird? Their iridescent feathers. 

  1. Chad M. Eliason, Julia A. Clarke. Cassowary gloss and a novel form of structural color in birdsScience Advances, 2020; 6 (20): eaba0187 DOI: 10.1126/sciadv.aba0187
  2. Dongyu Hu, Julia A. Clarke, Chad M. Eliason, Rui Qiu, Quanguo Li, Matthew D. Shawkey, Cuilin Zhao, Liliana D’Alba, Jinkai Jiang, Xing Xu. A bony-crested Jurassic dinosaur with evidence of iridescent plumage highlights complexity in early paravian evolutionNature Communications, 2018; 9 (1) DOI: 10.1038/s41467-017-02515-y
May 11, 2020

Episode 378 - Maple Syrup Golden tongues and antioxidants

Taste testing maple syrup and long lasting antioxidants. How do you judge the taste of something as complex as maple syrup? How can a golden tongue help find gold, silver and bronze maple syrups? Antioxidants can keep food fresh and wounds safe, so how can they be made long lasting? Tannic acid often found in wines can make great antioxidants, but how to make their chemical effect long lasting? Fine woven meshes embedded with antioxidants can help flexible wrap food and wounds to keep them safe.

  1. Simon Forest, Trevor Théorêt, Julien Coutu, Jean-Francois Masson. A high-throughput plasmonic tongue using an aggregation assay and nonspecific interactions: classification of taste profiles in maple syrupAnalytical Methods, 2020; DOI: 10.1039/C9AY01942A
  2. Adwait Gaikwad, Hanna Hlushko, Parvin Karimineghlani, Victor Selin, Svetlana A. Sukhishvili. Hydrogen-Bonded, Mechanically Strong Nanofibers with Tunable Antioxidant ActivityACS Applied Materials & Interfaces, 2020; 12 (9): 11026 DOI: 10.1021/acsami.9b23212
April 27, 2020

Episode 376 - Learning from spider webs, venom and combs

What can we learn from spiders webs, venom and combs? How do spiders manage to weave intricate webs without getting tangled in them? How can spider's legs help develop next generation nano materials? How can spider venom help us fight back against the opioid crisis? Spider venom is dangerous but it can also help reduce harm in pain management.

  1. Akello J. Agwa, Poanna Tran, Alexander Mueller, Hue N. T. Tran, Jennifer R. Deuis, Mathilde R. Israel, Kirsten L. McMahon, David J. Craik, Irina Vetter, Christina I. Schroeder. Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7Journal of Biological Chemistry, 2020; 295 (15): 5067 DOI: 10.1074/jbc.RA119.012281
  2. Anna-Christin Joel, Marco Meyer, Johannes Heitz, Alexander Heiss, Daesung Park, Hana Adamova, Werner Baumgartner. Biomimetic Combs as Antiadhesive Tools to Manipulate NanofibersACS Applied Nano Materials, 2020; 3 (4): 3395 DOI: 10.1021/acsanm.0c00130
  3. Po Peng, Devi Stuart‐Fox, Szu‐Wei Chen, Eunice J. Tan, Guan‐Lin Kuo, Sean J. Blamires, I‐Min Tso, Mark A. Elgar. High contrast yellow mosaic patterns are prey attractants for orb‐weaving spidersFunctional Ecology, 2020; DOI: 10.1111/1365-2435.13532
April 13, 2020

Episode 374 - Lasers, Metal and Insect wings vs Bacteria

Taking the fight to bacteria with lasers, metal and insect wings. How can lasers help make a material into a bacteria destroyer? Metal in fantasy has demon slaying properties, but how can it help fight bacteria? What can we learn from insect wings to help make safer implants? What is it about silver that makes it good for killing bacteria (and werewolves). Why are metals so dangerous for bacteria? How can we treat and use metal to make medical devices safer from bacteria?

  1. Vidhya Selvamani, Amin Zareei, Ahmed Elkashif, Murali Kannan Maruthamuthu, Shirisha Chittiboyina, Davide Delisi, Zheng Li, Lirong Cai, Vilas G. Pol, Mohamed N. Seleem, Rahim Rahimi. Hierarchical Micro/Mesoporous Copper Structure with Enhanced Antimicrobial Property via Laser Surface Texturing. Advanced Materials Interfaces, 2020; 1901890 DOI: 10.1002/admi.201901890
  2. Asmaa A. Sadoon, Prabhat Khadka, Jack Freeland, Ravi Kumar Gundampati, Ryan H. Manso, Mason Ruiz, Venkata R. Krishnamurthi, Suresh Kumar Thallapuranam, Jingyi Chen, Yong Wang. Silver Ions Caused Faster Diffusive Dynamics of Histone-Like Nucleoid-Structuring Proteins in Live Bacteria. Applied and Environmental Microbiology, 2020; 86 (6) DOI: 10.1128/AEM.02479-19
  3. J. Jenkins, J. Mantell, C. Neal, A. Gholinia, P. Verkade, A. H. Nobbs, B. Su. Antibacterial effects of nanopillar surfaces are mediated by cell impedance, penetration and induction of oxidative stress. Nature Communications, 2020; 11 (1) DOI: 10.1038/s41467-020-15471-x
April 6, 2020

Episode 373 - Deep sea reefs, ocean vents and tiny life

This week we look at unlikely partnerships that help sea creatures survive and thrive. What plays a crucial role inside a reef's ecosystem that is often overlooked? What's inside fish guts that help keep a reef healthy? Just how do fish 1000s of kms away end up with the same colonies of microbes? Feel like a tasty snack but stuck in the deep ocean vents, why not methane? How do microbes help worms eat methane? 

  1. Shana Goffredi et al. Methanotrophic bacterial symbionts fuel dense populations of deep-sea feather duster worms (Sabellida, Annelida) and extend the spatial influence of methane seepageScience Advances, 2020 DOI: 10.1126/sciadv.aay8562
  2. Jarrod J. Scott, Thomas C. Adam, Alain Duran, Deron E. Burkepile, Douglas B. Rasher. Intestinal microbes: an axis of functional diversity among large marine consumersProceedings of the Royal Society B: Biological Sciences, 2020; 287 (1924): 20192367 DOI: 10.1098/rspb.2019.2367
March 23, 2020

Episode 371 - Marine Mammals vs Parasites

Its a battle between Marine Mammals and Parasites. How does an opossum parasite start killing sea otters?  In #2020MMM unexpected combatants can ruin your day, just like how opossum parasites are taking out sea otters. How does a parasite make a long journey from land to end up out at sea? Inside raw fish, parasitic worm populations are booming. This is bad news for marine mammals. Conserving marine mammals can be a delicate balancing act as parasite populations can also start to thrive.

  1. Tristan L. Burgess, M. Tim Tinker, Melissa A. Miller, Woutrina A. Smith, James L. Bodkin, Michael J. Murray, Linda M. Nichol, Justin A. Saarinen, Shawn Larson, Joseph A. Tomoleoni, Patricia A. Conrad, Christine K. Johnson. Spatial epidemiological patterns suggest mechanisms of land-sea transmission for Sarcocystis neurona in a coastal marine mammaTlScientific Reports, 2020; 10 (1) DOI: 10.1038/s41598-020-60254-5
  2. Evan A. Fiorenza, Catrin A. Wendt, Katie A. Dobkowski, Teri L. King, Marguerite Pappaionou, Peter Rabinowitz, Jameal F. Samhouri, Chelsea L. Wood. It’s a wormy world: Meta-analysis reveals several decades of change in the global abundance of the parasitic nematodes Anisakis spp. and Pseudoterranova spp. in marine fishes and invertebratesGlobal Change Biology, 2020; DOI: 10.1111/gcb.15048
March 2, 2020

Episode 368 - Brain injuries, epilepsy and treatment options

How can we give better quality of life for those suffering from neurological conditions? Getting a concussion is bad enough, but why do people often develop epilepsy afterwards? What is the link between concussions and epilepsy? How can we effectively reduce the risk of epilepsy after a concussion? For certain epilepsy conditions in children, CBD can help reduce seizure risk, but what type is best? Is pharmaceutical or artisan CBD for children with epilepsy?

  1. Akshata A. Korgaonkar, Ying Li, Dipika Sekhar, Deepak Subramanian, Jenieve Guevarra, Bogumila Swietek, Alexandra Pallottie, Sukwinder Singh, Kruthi Kella, Stella Elkabes, Vijayalakshmi Santhakumar. Toll‐like Receptor 4 Signaling in Neurons Enhances Calcium‐Permeable α‐Amino‐3‐Hydroxy‐5‐Methyl‐4‐Isoxazolepropionic Acid Receptor Currents and Drives Post‐Traumatic EpileptogenesisAnnals of Neurology, 2020; DOI: 10.1002/ana.25698
  2. American Academy of Neurology. (2020, February 27). Artisanal CBD not as effective as pharmaceutical CBD for reducing seizures. ScienceDaily. Retrieved February 29, 2020 from www.sciencedaily.com/releases/2020/02/200227160545.htm
February 10, 2020

Episode 365 - Wasps, Bees, tasty meals and pesticide.

From wasps to bees how are insects adapting to a changing world. What type of food do bees prefer? Can a bee be a fussy eater? What makes a tasty meal for a Bee and what would they avoid like the plague? What changes can be introduced into the microbiome by pesticides? How can pesticides change the microbiome of wasps and develop into resistance? Can pesticide actually make lives harder for themselves by building tolerance in insects? How does an Asian hornet end up in Northern Europe?

  1. Wang et al. Changes in microbiome confer multigenerational host resistance after sub-toxic pesticide exposureCell Host & Microbe, 2020 DOI: 10.1016/j.chom.2020.01.009
  2. Martin Husemann, Andreas Sterr, Swen Mack, Rudolf Abraham. The northernmost record of the Asian hornet Vespa velutina nigrithorax (Hymenoptera, Vespidae)Evolutionary Systematics, 2020; 4 (1): 1 DOI: 10.3897/evolsyst.4.47358
  3. Fabian A. Ruedenauer, David Raubenheimer, Daniela Kessner‐Beierlein, Nils Grund‐Mueller, Lisa Noack, Johannes Spaethe, Sara D. Leonhardt. Best be(e) on low fat: linking nutrient perception, regulation and fitnessEcology Letters, 2020; DOI: 10.1111/ele.13454
February 3, 2020

Episode 364 - Coronavirus from SARS to MERs and nConv2019

The Coronavirus family is a dangerous lot from SARS to MERS and Novel Coronavirus 2019. This week we look at the history of Coronavirus outbreaks, research into past infections and public health strategy. We do some fact checking on Coronavirus myths and fears. What lessons were learnt from the SARS outbreak of '03 that can help today in '20? How can turning off the cells recycling plant stop Coronaviruses in their tracks? What role does cell autophagy play in spreading or stopping MERS? What can we learn from the sequenced genomes of coronaviruses? How can tracking the ACE2 gene help people monitor the mutation of the coronavirus strains?

  1. Lewis, D. (2020). Coronavirus outbreak: what’s next? Nature. doi: 10.1038/d41586-020-00236-9
  2. Hollingsworth, J. (2020, January 30). The memory of SARS looms over the Wuhan virus. Here's how the outbreaks compare. Retrieved from https://edition.cnn.com/2020/01/29/china/sars-wuhan-virus-explainer-intl-hnk-scli/index.html
  3. Alerts - Novel coronavirus - Frequently asked questions. (n.d.). Retrieved from https://www.health.nsw.gov.au/Infectious/alerts/Pages/coronavirus-faqs.aspx#1-1
  4. Coronavirus latest: WHO declares global emergency. (2020, January 30). Retrieved from https://www.nature.com/articles/d41586-020-00154-w
  5. Yushun Wan, Jian Shang, Rachel Graham, Ralph S. Baric, Fang Li. Receptor recognition by novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARSJournal of Virology, 2020; DOI: 10.1128/JVI.00127-20
  6. Nils C. Gassen, Daniela Niemeyer, Doreen Muth, Victor M. Corman, Silvia Martinelli, Alwine Gassen, Kathrin Hafner, Jan Papies, Kirstin Mösbauer, Andreas Zellner, Anthony S. Zannas, Alexander Herrmann, Florian Holsboer, Ruth Brack-Werner, Michael Boshart, Bertram Müller-Myhsok, Christian Drosten, Marcel A. Müller, Theo Rein. SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infectionNature Communications, 2019; 10 (1) DOI: 10.1038/s41467-019-13659-4