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498Episodes
Category: Science

A fun take on the latest science news with enough data to sink your teeth into. Lagrange Point goes beyond the glossy summary and gets in depth with the research from across the world.

January 31, 2022

Episode 468 - Stopping frostbite and bacteria using chemistry and physics

How can we protect skin from frostbite before it happens? Scientists freeze cells in the lab all the time, so how can that be used to help prevent frostbite? When treating frostbite minutes can make a huge difference. How can we improve prevention of the worst injuries from frostbite? You've heard of sunscreen but what about frostbite cream. Antiobiotic resistance is a serious issue, but what plasma could be a secret weapon. Using plasma we can engineer antimicrobial surfaces. Plasma sintered surfaces can wipe out bacteria.

  1. Aanchal Gupta, Betsy Reshma G, Praveen Singh, Ekta Kohli, Shantanu Sengupta, Munia Ganguli. A Combination of Synthetic Molecules Acts as Antifreeze for the Protection of Skin against Cold-Induced Injuries. ACS Applied Bio Materials, 2021; 5 (1): 252 DOI: 10.1021/acsabm.1c01058
  2. Anton Nikiforov, Chuanlong Ma, Andrei Choukourov, Fabio Palumbo. Plasma technology in antimicrobial surface engineering. Journal of Applied Physics, 2022; 131 (1): 011102 DOI: 10.1063/5.0066724
January 24, 2022

Episode 467 - Repairing throats and better implants

How can we make stronger implants that don't get rejected by the body? Bioactive materials can help make implants feel more at home. Replacing a knee or a hip requires not just strength but also compatibility. A new coating method makes it easier for implants to fit in. An implant has to be strong yet flexible, friendly to cells but not bacteria - it's challenging. Your vocal chords are subject to extreme forces, so how can we design an implant to repair them? Hydro-gels can help repair damaged organs and tissue even in extreme environments like your vocal chods.

  1. Imran Deen, Gurpreet Singh Selopal, Zhiming M. Wang, Federico Rosei. Electrophoretic deposition of collagen/chitosan films with copper-doped phosphate glasses for orthopaedic implantsJournal of Colloid and Interface Science, 2022; 607: 869 DOI: 10.1016/j.jcis.2021.08.199
  2. Sareh Taheri, Guangyu Bao, Zixin He, Sepideh Mohammadi, Hossein Ravanbakhsh, Larry Lessard, Jianyu Li, Luc Mongeau. Injectable, Pore‐Forming, Perfusable Double‐Network Hydrogels Resilient to Extreme Biomechanical StimulationsAdvanced Science, 2021; 2102627 DOI: 10.1002/advs.202102627
January 17, 2022

Episode 466 - Tsunamis, underwater volcanoes and magnetic fields

When Tsunami's strike, every extra minute of notice can help save lives. How can scientists better predict the height and journey of a tsunami? We look at the ways scientists can use tectonic plates or magnetic fields to improve tsunami predictions. Where an earthquake occurs can make a big difference to the size of a tsunami. The shallower an earthquake in a thinner sub-ducting plate can lead to higher tsunamis. When you move a large amount of sea-water the earths magnetic field changes, just enough to detect. Like reading the vibrations in seismic waves, earth's magnetic field changes enough for you to identify a tsunami. Using magnetic fields you can measure and asses the height of a tsunami much faster.

  1. Zhiheng Lin, Hiroaki Toh, Takuto Minami. Direct Comparison of the Tsunami‐Generated Magnetic Field With Sea Level Change for the 2009 Samoa and 2010 Chile TsunamisJournal of Geophysical Research: Solid Earth, 2021; 126 (11) DOI: 10.1029/2021JB022760
  2. Kwok Fai Cheung, Thorne Lay, Lin Sun, Yoshiki Yamazaki. Tsunami size variability with rupture depthNature Geoscience, 2021; DOI: 10.1038/s41561-021-00869-z
January 10, 2022

Episode 465 - Hedgehogs to mouthwash - Strange tales of the war against bacteria

From Hedgehogs to mouthwash, we check in on the arms race against bacteria. MRSA super-bugs are a super problem for humans, but some pre-date the modern era. MRSA super-bugs have been around since the Industrial revolution, at least on hedgehogs. The skin of hedgehogs is a battlefield between Fungus and Bacteria, and whoever wins, we loose. We often focus on Humans vs Bacteria, but it's actually a triple threat with Fungus. The fight Fungus vs Bacteria can lead to the development of antibiotic resistance. The mouth is the gate in the castle like defenses of the human immune system, so what defends it from bacteria attackers? If you have periodontal disease, it can make it easier for other viruses to get into your body. Keeping your mouth free of bacteria plaque can keep your defense against other infections high.

  1. Jesper Larsen, Claire L. Raisen, Xiaoliang Ba, Nicholas J. Sadgrove, Guillermo F. Padilla-González, Monique S. J. Simmonds, Igor Loncaric, Heidrun Kerschner, Petra Apfalter, Rainer Hartl, Ariane Deplano, Stien Vandendriessche, Barbora Černá Bolfíková, Pavel Hulva, Maiken C. Arendrup, Rasmus K. Hare, Céline Barnadas, Marc Stegger, Raphael N. Sieber, Robert L. Skov, Andreas Petersen, Øystein Angen, Sophie L. Rasmussen, Carmen Espinosa-Gongora, Frank M. Aarestrup, Laura J. Lindholm, Suvi M. Nykäsenoja, Frederic Laurent, Karsten Becker, Birgit Walther, Corinna Kehrenberg, Christiane Cuny, Franziska Layer, Guido Werner, Wolfgang Witte, Ivonne Stamm, Paolo Moroni, Hannah J. Jørgensen, Hermínia de Lencastre, Emilia Cercenado, Fernando García-Garrote, Stefan Börjesson, Sara Hæggman, Vincent Perreten, Christopher J. Teale, Andrew S. Waller, Bruno Pichon, Martin D. Curran, Matthew J. Ellington, John J. Welch, Sharon J. Peacock, David J. Seilly, Fiona J. E. Morgan, Julian Parkhill, Nazreen F. Hadjirin, Jodi A. Lindsay, Matthew T. G. Holden, Giles F. Edwards, Geoffrey Foster, Gavin K. Paterson, Xavier Didelot, Mark A. Holmes, Ewan M. Harrison, Anders R. Larsen. Emergence of methicillin resistance predates the clinical use of antibioticsNature, 2022; DOI: 10.1038/s41586-021-04265-w
  2. Carlos J. Rodriguez-Hernandez, Kevin J. Sokoloski, Kendall S. Stocke, Himabindu Dukka, Shunying Jin, Melissa A. Metzler, Konstantin Zaitsev, Boris Shpak, Daonan Shen, Daniel P. Miller, Maxim N. Artyomov, Richard J. Lamont, Juhi Bagaitkar. Microbiome-mediated incapacitation of interferon lambda production in the oral mucosaProceedings of the National Academy of Sciences, 2021; 118 (51): e2105170118 DOI: 10.1073/pnas.2105170118
January 3, 2022

Episode 464 - Rogue Planets and glass in meteorites

Rogue planets hurtling across space without a place to call home. How do we detect intergalactic nomads like Rogue planets? Just how many rogue planets are out there? Are there rogue planets lurking in our own solar system? Glass inside meteorites can help us understand early earth. How does meteorite rock differ from rock here on earth? What can we piece together about the cataclysmic events that formed glass inside meteorites? Rapidly heating then even more rapidly cooling coalesced glass inside meteorites.

  1. Núria Miret-Roig, Hervé Bouy, Sean N. Raymond, Motohide Tamura, Emmanuel Bertin, David Barrado, Javier Olivares, Phillip A. B. Galli, Jean-Charles Cuillandre, Luis Manuel Sarro, Angel Berihuete, Nuria Huélamo. A rich population of free-floating planets in the Upper Scorpius young stellar association. Nature Astronomy, 2021; DOI: 10.1038/s41550-021-01513-x
  2. Nicole X. Nie, Xin-Yang Chen, Timo Hopp, Justin Y. Hu, Zhe J. Zhang, Fang-Zhen Teng, Anat Shahar, Nicolas Dauphas. Imprint of chondrule formation on the K and Rb isotopic compositions of carbonaceous meteorites. Science Advances, 2021; 7 (49) DOI: 10.1126/sciadv.abl3929